GTSE1 Antilichaam

GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

51512

Q9NYZ3

Q9NYZ3

Human

This GTSE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 690-717 amino acids from the C-terminal region of human GTSE1.

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Mouse

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

77 kDa

Rabbit Ig

GTSE1

G2 and S phase-expressed protein 1

Homo sapiens

Bublik, D.R., et al. J. Biol. Chem. 285 (8) :5274-5281 (2010)

Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

Kapranov, P., et al. Genome Res. 15 (7) :987-997 (2005)

Cheng, J., et al. Science 308 (5725) :1149-1154 (2005)

G2 and S phase-expressed protein 1, GTSE-1, Protein B99 homolog, GTSE1

WB, IHC-P, Flow

317373439

Liquid