GW 796406
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GW 796406 is a novel vascular peptidase inhibitor. GW 796406’s inhibitory activity against NEP (IC50 ≈ 1.1-2.5 nM) is about three times that of ACE (IC50 ≈ 1.6-4.7 nM) . GW 796406 can be used for research on cardiovascular conditions[1].
581096-47-1
12352005
Angiotensin-converting Enzyme (ACE) ; Neprilysin
Metabolic Enzyme/Protease
Cardiovascular Disease
CC(C)[C@H](CS)C(N[C@H](C(O)=O)CC1=CC=C(N2C=CC=N2)C=C1)=O
C18H23N3O3S
361.46
[1]Sulpizio AC, et al. Mechanism of vasopeptidase inhibitor-induced plasma extravasation: comparison of omapatrilat and the novel neutral endopeptidase 24.11/angiotensin-converting enzyme inhibitor GW796406. J Pharmacol Exp Ther. 2005 Dec;315 (3) :1306-13.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19484/
Reference compound1
No Development Reported
Beschrijving
GW 796406 is a novel vascular peptidase inhibitor. GW 796406’s inhibitory activity against NEP (IC50 ≈ 1.1-2.5 nM) is about three times that of ACE (IC50 ≈ 1.6-
Specificaties
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