GW788388
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent inhibitor of TGF-β receptor kinases ALK4, ALK5 (IC50=18 nM), ALK7, and TGFβRII, but not BMP type II receptor kinase.1,2 Blocks TGF-β-mediated signaling, including collagen type I and VEGF, in turn reducing fibrosis and angiogenesis in various mouse models.3,4 GW788388 attenuates TGF-β-induced epithelial to mesenchymal transition (EMT) in human peritoneal mesothelial cells.5
Unconjugated
Off-white solid
-20°C
Beschrijving
GW788388 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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