Gyperine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with an IC50 of 18 μM, and its action is competitive with oleoyl-COA substrate, Ki value is 5.5 μM. Gypsetin also inhibits Oleic acid from forming cholesterol esters with an IC50 of 0.65 μM[1].
155114-38-8
12352005
Acyltransferase
Metabolic Enzyme/Protease
Metabolic Disease
C=CC(C)([C@]12[C@](C3=CC=CC=C3N1)(C[C@]4([H])N2C([C@@]5([H])N([C@@]6([C@](C5)(C7=CC=CC=C7N6)O)C(C)(C)C=C)C4=O)=O)O)C
C32H36N4O4
540.65
[1]B Nuber, et al. Gypsetin, a new inhibitor of acyl-CoA: cholesterol acyltransferase produced by Nannizzia gypsea var. incurvata IFO 9228. II. Structure determination. J Antibiot (Tokyo) . 1994 Feb;47 (2) :168-72.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N14715/
Natural Products
No Development Reported
Beschrijving
Gypsetin can inhibit acylcoenzyme A, cholesterol acyltransferase (ACAT) activity, inhibit rat liver microbody ACAT with an IC50 of 18 μM, and its action is comp
Specificaties
Recent bekeken producten
Anti-APOE2 mouse monoclonal antibody
TD-AB0132
100 µg
Human Apolipoprotein E2 (Apo E2) Antibody
22210-05011
150 µg
DiagPoly™ Carboxyl Fluorescent Polystyrene Particles, Green, 1 µm
DCFG-L007
1 mL
DiagPoly™ Carboxyl Polystyrene Particles, 1.0 µm
DNM-F029
10 mL
DiagPoly™ Carboxyl Fluorescent Polystyrene Particles, Green, 0.2 µm
DCFG-L004
1 mL
Optical EtBr filter, 610 nm for SmartView Pro Imager System, 1100 & 2100 series (for UV)
UVCI-1100-EB
1 Unit
AGPAT4 Antibody
MBS7124622-01
0.05 mL
H&E Mount, Permanent Mountindg media for coverslipping H&E stains from water,
NB315
125 mL
Recent gezochte producten
Anti-APOE2 mouse monoclonal antibody
TD-AB0132
100 µg
Human Apolipoprotein E2 (Apo E2) Antibody
22210-05011
150 µg
Pex7 (NM_008822) Mouse Untagged Clone
MC209163
10 µg
Pex7 (NM_008822) Mouse Tagged ORF Clone
MG223960
10 µg
Mouse Pex7 (NM_008822) AAV Particle
MR223960A1V
250 µL
Krt25 (NM_001008822) Rat Untagged Clone
RN212503
10 µg
Krt25 (NM_001008822) Rat Tagged ORF Clone
RR212503
10 µg
OACA12100-50UL
OACA12100-50UL
50 µL