GZMA Antilichaam - middelste regio : HRP (ARP54793_P050-HRP)

Granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

HFSP, CTLA3

3001

P12544

NP_006135

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human GZMA

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

HSP90AA1; HSPA4; HMGB2; APEX1; XRCC5; XRCC6; HIST2H2BE; SET; LMNA; HNRNPK; HDC; HIST1H1A; GZMA; GOLGA2; ACTG1; Ndufs3; NCL; LMNB1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

GZMA is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 85%; Dog: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 79%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

29kDa

Bem, R.A., (2008) Pediatr. Res. 63 (6), 650-655

Wet Ice

262

GZMA

GZMA

Rabbit

Granzyme A

NM_006144

TREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNS