H-2Dd-antilichaam [34-5-8S]

The monoclonal antibody 34-5-8S reacts with a conformational epitope on H-2Dd MHC Class I found on the N-terminal domains of alpha1 and alpha2 chains when complexed with beta2-microglobulin. The antibody does not react with H-2Dd alpha chains synthesized in vitro. Weak cross-reactivity with cells from mice of the H-2b, H-2q, and H-2s haplotypes has been observed by flow cytometric analysis. Reactivity with cells from mice of the H-2f, H-2k, H-2p, and H-2r haplotypes has not been observed. 34-5-8S has been reported to block the recognition of H-2Dd by Ly-49A+, Ly-49C+, and Ly-49G2+ natural killer cells.

14964

P01899

P01899

Mouse

BDF1 mouse splenocytes

[34-5-8S]

Unconjugated

Primary Antibodies

Cancer, Obesity, Signal Transduction

0.5 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

H-2Dd

H-2Dd Antibody [34-5-8S] for use in flow cytometry, immunocytochemistry, immunoprecipitation, ELISA, CMCD, blocking, purification, and adhesion assays.

H2-D1

Histocompatibility 2, D region locus 1

Mus musculus

MHC Class I

IHC-Fr, Flow

Liquid