H2B-antilichaam

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

8349

P33778

NP_003519.1

Human, Mouse, Rat

H2B antibody was raised against a peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

14 kDa

This antibody detects endogenous level of total H2B protein.

Western Blot: 1:500~1:1000

HIST2H2BE

Histone cluster 2, H2be

Homo sapiens

Borchert GM, et al. (2010) PLoS One. 5 (7) : e11641. Pennini ME, et al. (2010) PLoS Pathog. 6 (7) : e1000995. Lu C, et al. (2010) Sci China Life Sci. 53 (6) : 663-8.

H2B, H2BQ, GL105, H2B.1, H2BFQ, H2BGL105

WB

4504277

Liquid