HADHB Antilichaam

HADHB encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

3032

P55084

P55084

Human

This HADHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-342 amino acids from the C-terminal region of human HADHB.

Unconjugated

Primary Antibodies

Cancer, Obesity, Signal Transduction

This antibody is purified through a protein A column, followed by peptide affinity purification.

Batch dependent

Predicted species reactivity based on immunogen sequence: Bovine, Monkey

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

51 kDa

Rabbit Ig

HADHB

Trifunctional enzyme subunit beta, mitochondrial

Homo sapiens

Purevsuren, J., et al. Mol. Genet. Metab. 98 (4) :372-377 (2009)

Bogenhagen, D.F., et al. J. Biol. Chem. 283 (6) :3665-3675 (2008)

Wang, R., et al. Zhonghua Fu Chan Ke Za Zhi 41 (10) :672-675 (2006)

Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)

Trifunctional enzyme subunit beta, mitochondrial, TP-beta, 3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, HADHB

WB, Flow

116241345

Liquid