Harzianoside B

Harzianoside B is a diterpene aminoglycoside compound discovered from Trichoderma sp. SCSIOW21. Harzianoside B has the activity of inhibiting the production of NO. In the experiment with macrophage RAW 264.7 cells, its IC50 value is close to the maximum tested concentration of 100 µM. It can be used in the research of the anti-inflammatory field[1].

3075431-10-3

12352211

NO Synthase

Immunology/Inflammation

Inflammation/Immunology

OC/C(C[C@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O)/C=C(C)/CC2)=C\C[C@H]3C(C)(C)C2=C(C)CC3

C28H45NO7

507.66

[1]Li H, et al. Novel Sesquiterpene and Diterpene Aminoglycosides from the Deep-Sea-Sediment Fungus Trichoderma sp. SCSIOW21. Mar Drugs. 2022 Dec 22;21 (1) :7.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15508/

Natural Products

No Development Reported