HB-0017
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor, targeting IL-17A. HB-0017 inhibits the IL-6 secretion induced by IL-17A with an IC50 of 2.09 nM. HB-0017 significantly decreases ear thickness in Imiquimod -induced psoriasis-like mice model and alleviates inflammations in IL-17A-induced arthritis and air pouch mice model. The isotype control for the HB-0017 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
2790610-50-1
12352203
Interleukin Related
Immunology/Inflammation
COVID-19-immunoregulation
Inflammation/Immunology
[1]Xu JG, et al. Structural and functional insights into a novel pre-clinical-stage antibody targeting IL-17A for treatment of autoimmune diseases. Int J Biol Macromol. 2022 Mar 31;202:529-538.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991595/
Inhibitory Antibodies
No Development Reported
IL-17
Beschrijving
HB-0017 is a humanized IgG1κ monoclonal antibody inhibitor, targeting IL-17A. HB-0017 inhibits the IL-6 secretion induced by IL-17A with an IC50 of 2.09 nM. HB-
Specificaties
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