HB EGF (HBEGF) Mouse Monoclonal Antibody [Kloon ID: LBI10A4]

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]

Carrier-free (BSA/glycerol-free) HBEGF mouse monoclonal antibody, clone LBI10A4

DTR; DTS; DTSF; HEGFL

Homo sapiens heparin binding EGF like growth factor (HBEGF), mRNA.

1839

Q99075

Unconjugated

Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway

Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Secreted Protein, Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

HBEGF

https://www.ncbi.nlm.nih.gov/gene/?term=1839

https://www.uniprot.org/uniprot/Q99075