HBEGF Antilichaam - N-terminaal gebied: Biotine (ARP45201_P050-Biotine)

Heparin-binding EGF-like growth factor

DTR, DTS, DTSF, HEGFL

1839

Q99075

NP_001936

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N-terminal region of Human HBEGF

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Bag1; BCL6; ZBTB16; CD82; NRD1; LTBP3; ERBB4; MMP7; CD9; FBLN1; EGFR; HBEGF; CD44

Biotin

Polyclonal Antibody

WB

Affinity Purified

There is BioGPS gene expression data showing that HBEGF is expressed in PANC1

0.5 mg/ml

Cow: 100%; Dog: 86%; Guinea Pig: 79%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

22kDa

Wet Ice

208

HBEGF

HBEGF

Rabbit

Proheparin-binding EGF-like growth factor

NM_001945

FLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRKV