HBEGF Antilichaam/heparinebindende EGF-achtige groeifactor / DT-R

Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis.

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

Q99075

Human

A portion of amino acids 1-208 from human Heparin-binding EGF-like growth factor protein was used as the immunogen for the HBEGF antibody.

HBEGF/9503

IHC-P, WB

Protein G affinity

Purified

This HBEGF antibody is available for research use only.

Aliquot the HBEGF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Optimal dilution of the HBEGF antibody should be determined by the researcher.

Cell membrane, Membrane, Secreted

Western blot testing of mouse RAW264.7 cell lysate with HBEGF antibody. Predicted molecular weight ~23 kDa but may be observed at higher molecular weights due to glycosylation.