HBG1 Antilichaam

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1) . The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

3047

P69891

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HBG1 (NP_000550.2) .

Unconjugated

Primary Antibodies

Other

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 12kDa

IgG

HBG1

K-562

Mouse liver

Mouse lung

Rat liver

Rat lung

Hemoglobin subunit gamma-1

Homo sapiens

Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1

WB, IHC

Liquid