HBP1-eiwit, humaan, recombinant (GST)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16 (INK4A) promoter and activates p16 (INK4A) expression. We found that trichostatin A (TSA), an inhibitor of HDAC (histone deacetylase), induces p16 (INK4A) expression in an HBP1-dependent manner. HBP1 activates or represses the expression of some specific genes during cell growth and differentiation. HBP1 was acetylated by p3/CBP in two regions: repression domain (K297/35/37) and P domain (K171/419) . HBP1 acetylation after TSA treatment was confirmed by immunoprecipitation assay. HBP1 interacted with histone acetyltransferase p3 and CREB-binding protein (CBP) and also recruited p3/CBP to p16 (INK4A) promoter. HBP1 acetylation at K419 plays an important role in HBP1-induced p16 (INK4A) expression.
Ice Packs
-20°C
Beschrijving
HBP1-eiwit, humaan, recombinant (GST) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
Drug Stability Chamber
500-DSC102
1 Unit
Modular Incubator Chamber
MIC-101
1 Unit
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Recent gezochte producten
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
BDBV Nucleoprotein Recombinant Protein (N-His)
VK059012-01
50 µg
KBFP720 700L Stability Chamber
CHA3020
1 Each
KBFLQC240 247L Stability Chamber
CHA3022
1 Each
KBF1020 1020L Stability Chamber
CHA3024
1 Each
Stability Chamber KBFP240 247L
CHA3030
1 Each
Drug Stability Chamber
150-DSC100
1 Unit
Drug Stability Chamber
150-DSC200
1 Unit