HCAR1 Antilichaam / Hydroxycarbonzuurreceptor 1 / GPR81

HCAR1 is a G-protein coupled receptor that is primarily found in various tissues throughout the body, including the liver, adipose tissue, and skeletal muscle. When activated by its ligand, which in this case is a specific type of hydroxycarboxylic acid, HCAR1 plays a key role in regulating glucose and lipid metabolism. One of the most intriguing aspects of HCAR1 is its ability to promote the use of fats as an energy source, a process known as fatty acid oxidation. By activating HCAR1, the body is able to break down fatty acids more efficiently, leading to improved metabolic health and potentially aiding in weight management. Additionally, HCAR1 has been shown to have anti-inflammatory effects, which can help combat chronic inflammation associated with metabolic disorders such as obesity and diabetes. By modulating the body's immune response, HCAR1 can help reduce inflammation and improve overall health.

Western blot: 1:500-1:1000

Q9BXC0

Human

A portion of amino acids 287-316 from the human protein was used as the immunogen for the HCAR1 antibody.

WB

Antigen affinity

Purified

This HCAR1 antibody is available for research use only.

Aliquot the HCAR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

The stated application concentrations are suggested starting points. Titration of the HCAR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot testing of human 1) MCF7, 2) T-47D, 3) SK-BR-3 and 4) HepG2 cell lysate with HCAR1 antibody. Predicted molecular weight ~39 kDa.