HCN3 Polyklonale Antilichaam, AbBy FluorTM 488 Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Hyperpolarization-activated, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides. The HCN family consists of four members (HCN1-4), each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif. HCN channels are expressed in the brain, heart, thalamus and testis. The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart. HCN3 contains a segment characterized by a series of positively charged amino acids at every third position. This region designated S4 is likely to be the voltage sensor of the protein. In the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, respectively.
Hcn3; HCN3_HUMAN; hyperpolarization activated cyclic nucleotide-gated potassium channel 3; KIAA1535; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3.
57657
• Rabbit
Human
51-150/774
HCN3
• Polyclonal
• IgG
AbBy Fluor™ 488
KLH conjugated synthetic peptide derived from human HCN3
WB, IF (IHC-P)
Purified by Protein A.
499nm/519nm
1µg/µl
WB (1:300-5000), IF (IHC-P) (1:50-200)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
57657
Mouse, Rat, Cow, Horse, Rabbit
Beschrijving
HCN3 Polyklonale Antilichaam, AbBy FluorTM 488 Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
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