HDAC1 Antilichaam, KO gevalideerd

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

3065

Q13547

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

Affinity purification

293T

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 62kDa

IgG

HDAC1

HeLa

HepG2

MCF7

Mouse thymus

Mouse testis

Histone deacetylase 1

Homo sapiens

HDAC1 Antibody: HD1, RPD3, GON-10, RPD3L1, Histone deacetylase 1, HD1

WB, IHC, IF, IP

Liquid