HDAC2 (fosfo Ser394) Antilichaam

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes

3066

Q92769

NP_001518.2

Human, Mouse, Rat

HDAC2 (Phospho-Ser394) antibody was raised against a peptide sequence around phosphorylation site of serine 394 (E-D-S (p) -G-D) derived from Human HDAC2.

Unconjugated

Primary Antibodies

Phospho-Specific, Cell Cycle

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

60 kDa

This antibody detects endogenous level of HDAC2 only when phosphorylated at serine 394.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

HDAC2

Histone deacetylase 2

Homo sapiens

Tsai SC, et al. (2002) J Biol Chem; 277 (35) : 31826-33

HD2, RPD3, YAF1, PRKCT, HD2

WB, IHC, IF

116284376

Liquid