HDAC3 Antilichaam

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

8841

O15379

Human, Mouse, Rat

Recombinant protein of human HDAC3

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Stem Cell

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 49kDa

IgG

HDAC3

K-562

NIH/3T3

Mouse brain

Mouse spleen

Rat kidney

Histone deacetylase 3

Homo sapiens

HDAC3, RPD3, SMAP45, HD3, Histone deacetylase 3, RPD3-2

WB, IHC, IF, IP

Liquid