HDAC4 Antilichaam

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

9759

P56524

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 451-650 of human HDAC4 (NP_006028.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Immunology, Signal Transduction, Stem Cell

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 130kDa

IgG

WB: 1:500 - 1:2000

HDAC4

Mouse brain

Rat testis

Histone deacetylase 4

Homo sapiens

HDAC4, BDMR, AHO3, Histone deacetylase A, HD4, HA6116, HDAC-A, HDACA, Histone deacetylase 4, HDAC-4, KIAA0288

WB

Liquid