HDAC6 Antilichaam - N-terminalgebied: HRP (ARP31451_P050-HRP)

Histone deacetylase 6

HD6, JM21, CPBHM, PPP1R90

10013

Q9UBN7

AAH05872

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC6

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

HSP90B1; ACTB; UBC; TRIM50; MYH10; DYNC1H1; DDIT3; ELAVL1; MAPK3; MAPK1; RUNX2; TUBA1B; SUMO1; RANBP9; NEDD8; ADRB2; ATXN3; MEF2B; SQSTM1; HSP90AA1; RASSF2; SLMAP; SAV1; CTTNBP2NL; BAG3; SETD8; TUBB; HSPA8; HSPA6; HSPA5; HSPA4; HSPA2; HSPA1L; DNAJA1; ETV6

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, CHIP, IHC

Affinity Purified

There is BioGPS gene expression data showing that HDAC6 is expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

131kDa, 17 kD

Int J Mol Med. 2003 Jul;12 (1) :87-93.

Wet Ice

1215

HDAC6

HDAC6

Rabbit

HDAC6 protein EMBL AAH05872.1

NM_006044

VGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQ