HDAC6 (fosfo Ser22) Antilichaam

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes By similarity. Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.

10013

Q9UBN7

NP_006035.2

Human, Mouse

HDAC6 (phospho Ser22) antibody was raised against a peptide sequence around phosphorylation site of serine 22 (P-Q-S (p) -P-P) derived from Human HDAC6.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

131 kDa

IgG

The antibody detects endogenous level of HDAC6 only when phosphorylated at serine 22.

Western Blot: 1:500~1:1000

HDAC6

Histone deacetylase 6

Homo sapiens

Chen S, Owens GC, Makarenkova H, Edelman DB (2010) PLoS One 5, e10848.

HD6, HDA6, Histone deacetylase 6, JM21

WB

13128864

Liquid