HDAC7A (fosfo Ser155) Antilichaam

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

51564

Q8WUI4

NP_056216.2

Human, Mouse

HDAC7A (phospho Ser155) antibody was raised against a peptide sequence around phosphorylation site of Serine 155 (T-V-S (p) -E-P) derived from Human HDAC7A.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

103 kDa

IgG

The antibody detects endogenous levels of HDAC7A only when phosphorylated at serine 155.

Western Blot: 1:500~1:1000

HDAC7

Histone deacetylase 7

Homo sapiens

Walsh M.J., Submitted (FEB-2000) .

Zelent A., Submitted (MAY-2003) .

Sugano S., Nat. Genet. 36:40-45 (2004)

HD7a, HDA7, HDAC7A

WB

30913097

Liquid