HDAC8 Antilichaam - C-terminalgebied: HRP (ARP34587_P050-HRP)

Histone deacetylase 8

HD8, WTS, RPD3, CDA07, CDLS5, KDAC8, MRXS6, HDACL1

55869

Q9BY41

NP_060956

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC8

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

MDM1; HDAC8; ZSCAN2; CHCHD3; STAG2; SEC16A; CROCC; SMC3; CPNE3; SMC1A; TPM4; TPM3; SVIL; NUP98; MME; ADD3; SMG5; SMG6; HSP90AA1; HSPA4; HIST4H4; HIST3H3; UBC; PRKACA; HIST1H4A; HIST1H3A; ESRRA; ACTA1; RTN1; PPP1CC; CREB1; HIST2H4A; RUNX1T1; CBFA2T3; MDC1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

42kDa

Lee, H., et al., (2004) Mol. Cell. Biol. 24 (2), 765-773

Wet Ice

377

HDAC8

HDAC8

Rabbit

Histone deacetylase 8

NM_018486

TGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNY