HDAC8 Antilichaam - N-terminalgebied: FITC (ARP34586_P050-FITC)

Histone deacetylase 8

HD8, WTS, RPD3, CDA07, CDLS5, KDAC8, MRXS6, HDACL1

55869

Q9BY41

NP_060956

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC8

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

MDM1; HDAC8; ZSCAN2; CHCHD3; STAG2; SEC16A; CROCC; SMC3; CPNE3; SMC1A; TPM4; TPM3; SVIL; NUP98; MME; ADD3; SMG5; SMG6; HSP90AA1; HSPA4; HIST4H4; HIST3H3; UBC; PRKACA; HIST1H4A; HIST1H3A; ESRRA; ACTA1; RTN1; PPP1CC; CREB1; HIST2H4A; RUNX1T1; CBFA2T3; MDC1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 86%; Dog: 86%; Guinea Pig: 91%; Horse: 93%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 79%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

42kDa

Balasubramanian, S., (2008) Leukemia 22 (5), 1026-1034

Wet Ice

377

HDAC8

HDAC8

Rabbit

Histone deacetylase 8

NM_018486

MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYAL