HDAC8 Mouse Monoclonal Antibody [Kloon ID: LBI1B2]

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Carrier-free (BSA/glycerol-free) HDAC8 mouse monoclonal antibody, clone LBI1B2

CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS

Homo sapiens histone deacetylase 8 (HDAC8), transcript variant 1, mRNA.

55869

Q9BY41

Unconjugated

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

HDAC8

https://www.ncbi.nlm.nih.gov/gene/?term=55869

https://www.uniprot.org/uniprot/Q9BY41