HDGFRP2 Antilichaam

HDGFRP2 Antibody: Hepatoma-derived growth factor-related protein 2 (HDGFRP2) is a widely expressed member of protein family that contains the HDGF related proteins 1-4 and lens epithelial derived growth factor (LEDGF) . These family members show extensive homology at the amino terminus (termed the hath region) . Little is known of the role of HDGFRP2, but like the related LEDGF, HDGFRP2 can bind HIV-1 integrase and stimulate HIV-1 integrase activity in vitro.

84717

Q7Z4V5

EAW69215

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

HDGFRP2 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1462 - Rat Lung Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Chicken: (94%)

HDGFRP2 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

HDGFRP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members

HDGFRP2

Hepatoma-derived growth factor-related protein 2

Homo sapiens

El-Tahir HM, Dietz F, Dringen R, et al. Expression of Hepatoma-derived growth factor family members in the adult central nervous system. BMC Neurosci. 2006; 7:6.

Izumoto Y, Kuroda T, Harada H, et al. Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus. Biochem. Biophys. Res. Commun. 1997; 238:26-32

Cherepanov P, Devroe E, Silver PA, et al. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. J. Biol. Chem. 2004; 279:48883-92.

HDGFRP2 Antibody: HDGF2, HDGF2, UNQ785/PRO1604, Hepatoma-derived growth factor-related protein 2, Hepatoma-derived growth factor 2, HRP-2

ELISA, WB, IHC-P, IF

48255931

Liquid