HEBP1 Polyklonale Antilichaam, PE-vervoeging

P22HBP, also known as HEBP1 (heme binding protein 1), HBP or HEBP, is a 189 amino acid intracellular tetrapyrrole-binding protein that assists in prevention of cellular toxicity by removing free porphyrinogens from the cell. Existing as a monomer, p22HBP localizes to cytoplasm and contains a 21 amino acid chemoattractant within its N-terminus that functions as a natural ligand for FPR3. p22HBP is a member of the HEBP family and binds N-methylprotoporphyrin and metalloporphyrins with similar affinity to porphyrinogens. The gene encoding p22HBP maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

HBP; HEBP; Hebp1; HEBP1_HUMAN; Heme binding protein 1; Heme-binding protein 1; p22HBP.

50865

Rat

51-150/189

HEBP1

PE

KLH conjugated synthetic peptide derived from human HEBP1/p22HBP

WB, IF (IHC-P)

Purified by Protein A.

496,564nm/578nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

50865

Human, Mouse, Dog, Pig, Horse, Rabbit