HECA Polyklonale Antilichaam, PE-Cy5,5 Vervoeging

HECA, also known as headcase homolog, HDC, HDCL or HHDC, is a 543 amino acid mammalian homolog of the Drosophila headcase protein, a highly basic, cytplasmic peptide that plays a role in mitotic re-entry during adult morphogenesis. Expressed in a variety of tissues with highest expression in thymus, spleen and heart, HECA is thought to play a role in the development of epithelial tube networks in lung tissue and may also be involved in the pathogenesis of lung cancer. The gene encoding HECA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

HDCL; Gm869; HDC; HDC_HUMAN; Headcase homolog Drosophila; Headcase protein homolog; HECA; hHDC.

51696

Q9UBI9

Human, Mouse, Rat

231-330/543

HECA

PE-Cy5.5

KLH conjugated synthetic peptide derived from human HECA

WB

Purified by Protein A.

488nm/694nm

1µg/µl

WB (WB=1:500-2000)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

51696