HELLS Antilichaam / PASG / Lymfoïde-specifieke helicase

Lymphoid-specific helicase (Lsh), also called PASG and SMARCA6, is a member of the SNF2 helicase family of chromatin remodeling proteins that in humans is encoded by the HELLS gene. This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Western blot: 1-2 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

Q9NRZ9

Human, Mouse

An E.coli-derived human recombinant protein (amino acids N167-F838) was used as the immunogen for the HELLS antibody.

WB, IF, FACS, ELISA

Antigen affinity chromatography

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This HELLS antibody is available for research use only.

After reconstitution, the HELLS Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the HELLS antibody should be determined by the researcher.

Immunofluorescent staining of FFPE human HeLa cells with HELLS antibody (red) and Beta Tubulin mAb (green) . HIER: steam section in pH6 citrate buffer for 20 min.