Hepsulfam (standaard)

Hepsulfam (NCI 329680; ZINC01574758) is a anticancer agent that shows excellent antileukemic activity with an median IC50 of 0.91 μg/mL in a panel of different tumors.

96892-57-8

12352211

DNA Alkylator/Crosslinker

Cell Cycle/DNA Damage

Cancer

O=S(OCCCCCCCOS(=O)(N)=O)(N)=O

C7H18N2O6S2

290.36

[1]Berger DP, et al. Preclinical activity of hepsulfam and busulfan in solid human tumor xenografts and human bone marrow. Anticancer Drugs. 1992 Oct;3 (5) :531-9.|[2]Pacheco DY, et al. Mechanisms of toxicity of hepsulfam in human tumor cell lines. Cancer Res. 1990 Dec 1;50 (23) :7555-8.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-U00095R/

Reference Standards