Heptaibin

Heptaibin is a peptaibol antifungal antibiotic. Heptaibin has the activity against Gram-positive bacteria (MIC is 8 μg/mL) such as Staphylococcus aureus and fungi (MIC is 13-32 μg/mL) such as Aspergillus, Candida albicans and cryptococcus neofordii, and it has moderate anti-Rhabditella pseudoelongata activity (MIC is 50 μg/mL) [1].

291311-47-2

12352005

Antibiotic; Fungal

Anti-infection

Infection

O=C(N1[C@@H](C[C@H](C1)O)C(NC(C)(C)C(N[C@H](CO)CC2=CC=CC=C2)=O)=O)C(C)(C)NC([C@H](CCC(N)=O)NC([C@H]3N(C[C@@H](C3)O)C(C(C)(C)NC(C(C)(C)NC([C@H](CC(C)C)NC(CNC([C@H](C(C)C)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@@H](NC(C)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

C76H118N16O19

1559.85

[1]D Ishiyama, et al. Heptaibin, a novel antifungal peptaibol antibiotic from Emericellopsis sp. BAUA8289. J Antibiot (Tokyo) . 2000 Jul;53 (7) :728-32.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14685/

Natural Products

No Development Reported