HER2 (fosfo-Tyr1112) Antilichaam

Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.

2064

P04626

NP_001005862.1

Human, Mouse, Rat

HER2 (phospho Tyr1112) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1112 (Q-R-Y (p) -S-E) derived from Human HER2.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

150 kDa

IgG

The antibody detects endogenous level of HER2 only when phosphorylated at tyrosine 1112.

Western Blot: 1:500~1:1000

ERBB2

V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2

Homo sapiens

Chuang TD, et al. (2010) J Biol Chem 285, 23598-606

Bhuvaneswari R, Gan YY, Soo KC, Olivo M (2009) Mol Cancer 8, 94

Thelemann A, et al. (2005) Mol Cell Proteomics 4, 356-76

C-erbB-2, NGL, NEU proto-oncogene, MLN 19

WB

54792098

Liquid