HERC5 Antilichaam

This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.

51191

Q9UII4

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human HERC5 (NP_057407.2) .

Unconjugated

Primary Antibodies

Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 117kDa

IgG

WB: 1:500 - 1:2000

HERC5

OVCAR3

HT-1080

Mouse kidney

Rat testis

HECT and RLD domain containing E3 ubiquitin protein ligase 5

Homo sapiens

HERC5, CEB1, CEBP1

WB

Liquid