Hercombinatie Androden Receiver (CT)

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.9 Publications Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones.

Androgen Receptor

P10275

Human; Rat; Mouse

Synthetic peptide derived from Androgen Receptor (AR) (C-term) anti

HYSP; NR3C; SMAX; AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM; AR; AIS; AR8; DHTR; HUMARA; HYSP1; KD; NR3C4; SBMA; SMAX1; TFM; AR; Group C; Member 4; Nuclear Receptor Subfamily 3

A132

Unconjugated

WB; IHC

Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Developmental Biology

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/rDuIxVHV

99 kDa

120 kDa

IgG, κ