Hercombinatie CDK1 / Cdc2

CDC2, also named as CDK1, belongs to the protein kinase superfamily. The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of cdc2 at Thr161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of cdc2 at Thr14 and Tyr15. Phosphorylation at Thr14 and Tyr15, resulting in inhibition of cdc2, can be carried out by Wee1 and Myt1 protein kinases.

CDK1/Cdc2

P06493

Human; Rat; Mouse; African green monkey

Recombinant human CDK1/Cdc2 fragment

CDC; CDK; CDKN; cyclin-dependent kinase; P34CDC; CDK1; CDC2; CDC28A; P34CDC2; cyclin-dependent kinase 1; CDKN1; CDC2; CDC28A; cyclin-dependent kinase 1; P34CDC2; cyclin dependent kinase 1874

A685

Unconjugated

WB; IHC; IF; FCM

Cell Biology; Epigenetics and Nuclear Signaling; Cancer; Neuroscience; Metabolism

Protein A purified

1 mg/mL

WB 1:1000; IHC 1:50-1:100; IF 1:50-1:100; FCM 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/uv44EFQ6

34 kDa

34 kDa

IgG, κ