Hes1 Antibody - C-terminal regio : HRP (ARP31970_P050-HRP)

Hairy and enhancer of split 1 (Drosophila)

Hes1

29577

Q04666

NP_077336

Human, Mouse, Rat, Cow, Guinea Pig, Pig, Rabbit

The immunogen is a synthetic peptide corresponding to a region of Rat

Hes1 is the transcriptional repressor of genes that require a bHLH protein for their transcription. Hes1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.

Polr2a; Kat2b; Sfpq; Src; Crebbp; Parp1; Camk2a

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

30kDa

Wet Ice

281

HES1

Hes1

Rabbit

Transcription factor HES-1

NM_024360

AFLIPNGAFAHSGPVIPVYTSNSGTSVGPNAVSPSSGSSLTADSMWRPWR