Hexacyclinol
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Hexacyclinol has moderate anti-Gram-positive bacteria activity, 4-40 μg/mL can inhibit the production of oxidants by polymorphonuclear neutrophils (PMNL) stimulated by zymosan. Hexacyclinol inhibits the growth of L-930 and K 562 cells with IC50s of 1.4 μg/mL and 0.4 μg/mL, respectively, and the IC50 of HeLa cells is 10 μg/mL. Hexacyclinol also has an anti-Plasmodium effect, and its IC50 for Plasmodium falciparum is 2.4 μg/mL[1].
903574-41-4
12352005
Bacterial; Parasite
Anti-infection
Cancer; Infection
COC(C)([C@@H]1[C@@]23[C@@]([C@@]4([H])C(C([C@]5([H])[C@](O5)([H])[C@@H]4O)=O)=C1)([H])[C@@]([C@@]6([H])[C@@](O6)([H])C3=O)([H])O[C@@H]2/C=C(C)\C)C
C23H28O7
416.46
[1]David M Pinkerton, et al. (+) -hexacyclinol. Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 13;66 (Pt 2) :o342-3.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N14970/
Natural Products
No Development Reported
Beschrijving
Hexacyclinol has moderate anti-Gram-positive bacteria activity, 4-40 μg/mL can inhibit the production of oxidants by polymorphonuclear neutrophils (PMNL) stimul
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