
HEXDC Polyklonale Antilichaam, Biotin Vervoeging
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Beta hexosaminidase D; Beta N acetylhexosaminidase; FLJ23825; Hexosaminidase glycosyl hydrolase family 20 catalytic domain containing; hexosaminidase glycosyl hydrolase family 20, catalytic domain; Hexosaminidase D; Hexosaminidase domain containing protein; N acetyl beta galactosaminidase; HEXDC_HUMAN.
284004
Cytoplasm, Nucleus
• Rabbit
Human
1-100/486
HEXDC
• Polyclonal
• IgG
Biotin
KLH conjugated synthetic peptide derived from human HEXDC
WB, ELISA, IHC-P, IHC-F
Purified by Protein A.
1µg/µl
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Unmodified
Store at -20°C for 12 months.
284004
Mouse, Rat, Dog, Horse
Beschrijving
HEXDC Polyklonale Antilichaam, Biotin Vervoeging Beschikbaar in 100 µL. Bestel eenvoudig online met snelle levering.
Specificaties
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