HEY2 Antilichaam

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

23493

Q9UBP5

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1) .

Unconjugated

Primary Antibodies

Stem Cell, Transcription

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 36kDa

IgG

WB: 1:500 - 1:2000

HEY2

K562

MCF7

Mouse brain

Rat heart

Hes-related family bHLH transcription factor with YRPW motif 2

Homo sapiens

HEY2, OTTHUMP00000017138, MGC10720, HRT2, HES-related repressor protein 1, HESR2, HERP1, hairy-related transcription factor 2, hairy/enhancer-of-split related with YRPW motif 2, GRL, GRIDLOCK, CHF1, cardiovascular basic helix-loop-helix factor 1, bHLHb32, BHLHB32, HERP

WB

Liquid