HGF Antilichaam

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

3082

P14210

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 30-285 of human HGF (NP_001010933.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Growth Factors, Signal Transduction

Affinity purification

Mouse liver

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 110kDa

IgG

HGF

Rat liver

Hepatocyte growth factor (hepapoietin A; scatter factor)

Homo sapiens

HGF, F-TCF, HGFB, HPTA, SF, DFNB39

WB, IHC

Liquid