HIF-1 alfa (HIF1A) Mouse Monoclonal Antibody [Kloon ID: LBI2D5]

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]

Carrier-free (BSA/glycerol-free) HIF1A mouse monoclonal antibody, clone LBI2D5

BHLHe78; HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8

Homo sapiens hypoxia inducible factor 1 subunit alpha (HIF1A), transcript variant 1, mRNA.

3091

Q16665

Unconjugated

MTOR signaling pathway, Pathways in cancer, Renal cell carcinoma

MTOR signaling pathway, Pathways in cancer, Renal cell carcinoma

WB 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Transcription Factors

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

HIF1A

https://www.ncbi.nlm.nih.gov/gene/?term=3091

https://www.uniprot.org/uniprot/Q16665