HIF3 alfa (HIF3A) (NM 152795) Humaan Recombinant Proteïne

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia) . The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]

Purified recombinant protein of Human hypoxia inducible factor 3, alpha subunit (HIF3A), transcript variant 3, Gln355-End, with N-terminal His tag, expressed in E. coli, 50ug

BHLHe17; HIF-3A; HIF3-alpha-1; IPAS; MOP7; PASD7

64344

Q9Y2N7

NM_152795

19q13.32

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.

Druggable Genome, Transcription Factors

33.6 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

HIF3A

Human

NP_690008

https://www.ncbi.nlm.nih.gov/gene/64344

https://www.uniprot.org/uniprot/Q9Y2N7

https://www.ncbi.nlm.nih.gov/nuccore/NM_152795

https://www.ncbi.nlm.nih.gov/nuccore/NP_690008