HIF3A Antilichaam - C-terminaal gebied: Biotine (ARP39936 T100-Biotine)

Hypoxia inducible factor 3, alpha subunit

IPAS, MOP7, PASD7, HIF-3A, bHLHe17, HIF3-alpha-1

64344

Q9Y2N7

NP_690007

Human

The immunogen is a synthetic peptide directed towards the C terminal region of human HIF3A

HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia) . The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression.The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia) . The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene.

HSP90AA1; VHL; EGLN3; EGLN1; EGLN2; HIF1A

Biotin

Polyclonal Antibody

IHC, WB

There is BioGPS gene expression data showing that HIF3A is expressed in HepG2

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

72kDa

Kimura, K., (2006) Genome Res. 16 (1), 55-65

Wet Ice

667

HIF3A

HIF3A

Rabbit

Hypoxia-inducible factor 3-alpha

NM_152794

PGSLQDPSTPLLNLNEPLGLGPSLLSPYSDEDTTQPGGPFQPRAGSAQAD