HIST2H2AC Antilichaam - middelste regio : HRP (ARP51480 T100-HRP)

Histone cluster 2, H2ac

H2A, H2A/q, H2AFQ, H2A-GL101, HIST2H2AC

8338

Q16777

NP_003508

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AC

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AC is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

BAP1; UBC; RNF2; INO80; UIMC1; RAD6; HDAC2; USP16; AURKB; NEDD8; CUL4A; USP15; SART3; HIST2H2BE; POLR2C; RNF168; HCVgp1; PRAME; RNF8; CRP; CENPA; HIST1H3B; EP300; KAT2A; BRCA1; BARD1; RBBP7; RBBP4; HAT1; ATXN7L3; USP22; MECP2; CHFR; DDB2; HIST1H4A; HIST1H

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

14kDa

Zhao, Y., (2008) Mol. Cell 29 (1), 92-101

Wet Ice

129

HIST2H2AC

HIST2H2AC

Rabbit

Histone H2A type 2-C

NM_003517

IPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHKAKSK