Histone deacetylase 4 Adenovirus (Ad-HDAC4)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is a critical process in transcriptional regulation, and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the N-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility of transcription factors to DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Mammalian nuclear histone acetylases include GCN5, PCAF (p300/CBP-associated factor), HAT1, MOF, HBO, MOZ, MORF and TIP60.1.
Histone deacetylase 4 Adenovirus
41106621
3822190000
Pre-Made
Dry Ice
-80C
12 Months
Ad-HDAC4
Human Adenovirus Type5 (dE1/E3)
CMV (ubiquitous)
DMEM, 2% BSA, 2.5% Glycerol
1x10^10 PFU/ml
Beschrijving
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is a critical process in tran
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