Histone H2AX Antilichaam

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

3014

P16104

Human, Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human Histone H2AX (NP_002096.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 16kDa

IgG

H2AFX

MCF-7

NIH/3T3

Raji

Mouse testis

Mouse thymus

H2A histone family, member X

Homo sapiens

H2AFX, H2A.X, H2A/X, H2AX

WB, IHC, IF

Liquid