Histone H3.1 (Ab 10) Antilichaam

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

8351

P68431

NP_003521.2

Human, Mouse, Rat

Histone H3.1 (Ab-10) antibody was raised against a peptide sequence around aa.8~12 (R-K-S-T-G) derived from Human Histone H3.1.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

17 kDa

This antibody detects endogenous level of total Histone H3.1 protein.

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

HIST1H3D

Histone cluster 1, H3d

Homo sapiens

Workman, J. L. and Kingston, R. E. (1998) Annu Rev Biochem 67, 545-79. Hansen, J. C. et al. (1998) Biochemistry 37, 17637-41. Strahl, B. D. and Allis, C. D. (2000) Nature 403, 41-5. Cheung, P. et al. (2000) Cell 103, 263-71.

H3/b, H3FB, H3/a, H3/c, H3/d, H3/f, H3/h

WB, IF

21071021

Liquid