HIV-1 p24 Antilichaam [8G9] (HRP)

HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1) . The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17), capsid (p24), nucleocapsid (p7) and the p6 protein (2) . The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3) .

155030

P04591

AAB50258

Virus

Mouse monoclonal HIV-1 p24 antibody was raised against a recombinant full-length HIV-1 p24 protein.

8G9

HRP

Primary Antibodies

Infectious Disease

HIV-1 p24 antibody is supplied as protein A purified IgG1.

Cat. No. 95-153 - Recombinant HIV-1 p24

1 mg/mL

HIV-1 p24 antibody is supplied in PBS containing 1% BSA and 0.02% thimerosol.

None

Blue Ice

HIV-1 p24 Monoclonal Antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

Predicted: 24, 41, 55 kDa

IgG1

By Western blot, anti-HIV-1 p24 antibody detects a ~24 kDa, a ~41 kDa, and a ~55 kDa protein, corresponding to HIV-1 p24 and to its precursors p41 and p55, respectively, in HIV-1 samples.

PM-6335-HRP can be used for detection of p24 by Western blot or ELISA at 0.2 – 0.5μ g/mL.

GAG

Gag Pr55 (Gag)

Hiv-1

Goto T, Nakai M, and Ikuta K. The life-cycle of human immunodeficiency virus type 1. Micron 1998; 29:123-38.

Freed EO. HIV-1 gag proteins: diverse functions in the virus life cycle. Virology 1998; 251:1-15.

Flynn BJ, Kastenmuller K, Wille-Reece U, et al. Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates. Proc. Natl. Acad. Sci. USA 2011; 108:7131–6.

HIV-1 p24 Antibody [8G9] :

ELISA, WB

327745

Liquid